Resolution of Iris Neovascularization Following Chemoreduction of Advanced Retinoblastoma
نویسندگان
چکیده
منابع مشابه
Resolution of iris neovascularization following chemoreduction of advanced retinoblastoma.
Iris neovascularization (NVI) in eyes with newly diagnosed retinoblastoma is a hallmark of advanced tumor. These eyes often display secondary glaucoma and additional partial or complete retinal detachment. From a clinical perspective, NVI with secondary glaucoma is noted in approximately 12% of eyes with retinoblastoma, and from a pathology perspective, NVI has been found in 44% of eyes followi...
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OBJECTIVE To evaluate conservative management of unilateral retinoblastoma using chemoreduction and focal treatment. DESIGN Prospective nonrandomized single-center clinical trial. SETTING Ocular Oncology Service at Wills Eye Hospital of Thomas Jefferson University, Philadelphia, Pa, in conjunction with the Division of Oncology at The Children's Hospital of Philadelphia. PARTICIPANTS Thirt...
متن کاملEvolution in regression patterns following chemoreduction for retinoblastoma.
OBJECTIVE To evaluate the change in regression pattern following chemoreduction and tumor consolidation therapy (thermotherapy or cryotherapy) for retinoblastoma METHODS Retrospective medical record analysis was completed for 557 retinoblastomas (239 eyes of 157 patients) that were treated with chemoreduction and showed regression to 1 of 5 patterns (type 0, no visible remnant; type 1, comple...
متن کاملLong-term visual outcome following chemoreduction for retinoblastoma.
OBJECTIVE To evaluate long-term visual outcome following chemoreduction. DESIGN Interventional case series evaluating 54 eyes of 40 children with retinoblastoma successfully treated with chemoreduction, consisting of a combination of intravenous carboplatin, etoposide phosphate, and vincristine sulfate plus focal therapy without external beam radiotherapy or enucleation. All patients were fol...
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BACKGROUND Primary chemotherapy is a new treatment approach in retinoblastoma, aiming to avoid radiogenic adverse effects, such as second tumor-associated mortality, as observed following external beam irradiation. OBJECTIVE To describe the clinical and histopathologic regression pattern after primary chemotherapy in retinoblastoma. METHODS Five patients with sporadic bilateral retinoblasto...
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ژورنال
عنوان ژورنال: Archives of Ophthalmology
سال: 2006
ISSN: 0003-9950
DOI: 10.1001/archopht.124.8.1196